5HTP

For Mood and Sleep

5HTP is a botanical product that is derived from the seed of the plant Griffonia simplicifolia, It is often used for its positive effects on mood and sleep. It promotes the formation of serotonin and melatonin in the body. 5HTP may also improve chronic pain symptoms in patients  with conditions such as fibromyalgia.  It can decrease appetite and is sometimes used for weight loss.

Doses

5HTP is usually used in doses of 100 mg, 2–3 times daily. When used in the short term, 5HTP can be very effective, though some studies show that using it for long periods can diminish its effectiveness.

Warnings

5HTP can increase serotonin levels in the body, and in very large doses it can lead to a life-threatening condition called serotonin syndrome. When used at appropriate doses, it is generally safe. Many medications, including anti-depressants and some sleep aids, also increase serotonin, which could lead to dangerous or even life-threatening levels. Certain nutritional supplements, such as SAM-E, also increase serotonin levels. 5HTP can also interfere with the metabolism of many pharmaceutical medications. If you are taking anti-depressants, sleeping aids, certain pain medications such as Tramadol, or dietary supplements, please consult a trusted integrative medical provider or pharmacist to ensure safety before starting 5HTP.

The most common side effects include gastrointestinal (GI) discomfort and decreased appetite.